热烈祝贺曾小明教授及学生发表高水平文章

黄河长江

   7月14日，前沿院有机化学研究中心博士生韦玉（导师：曾小明博士）以第一作者身份在国际化学领域期刊《美国化学会志》（J. Am. Chem. Soc.，影响因子12.113）上在线发表题为“Highly Selective Hydrogenation of Aromatic Ketones and Phenols Enabled by Cyclic (Amino)(alkyl)carbene Rhodium Complexes”的最新研究成果。该文章第一作者与通讯作者单位均为西安交通大学。

    选择性氢化是化学工业中最重要的一类合成反应之一，被广泛应用于构筑与人们生活密切相关的药物及材料化合物。相对于活泼的羰基而言，芳香性的苯环难以发生氢化反应。目前该领域的研究多局限于氢化羰基而保留惰性的芳环骨架。该课题组以环状单胺基卡宾为配体，成功翻转这类化学反应的选择性。首次实现高选择性地均相催化苯环及苯酚的氢化，有效地保留活泼的羰基。该催化体系表现出良好的官能团兼容性，能够以十克级的规模放大进行而不影响反应选择性与收率，为化学工业上制备环已基酮类化合物提供了一条高效、洁净的合成路径。

   该研究得到了国家自然科学基金的支持。

  曾小明老师近年来连续在化学顶级国际期刊上发表文章多篇，彰显了其个人超强的有机合成造诣。笔者当年曾经在其实验组做研究1个月，曾老师思维慎密，富有钻研精神，这些都是我值得学习的地方，衷心祝愿他的科研事业更上一层楼！
Representative Publications

1.   Xuefeng Cong, Yuexuan Li, Yu Wei and Xiaoming Zeng*
       Nickel-Catalyzed C–H Coupling with Allyl Phosphates: A Site-Selective Synthetic Route to Linear Allylarenes
       Org. Lett., 2014,16, 3916–3929. [Link]
2.   Xuefeng Cong and Xiaoming Zeng*
       Iron-Catalyzed, Chelation-Induced Remote C–H Allylation of Quinolines via 8-Amido Assistance
       Org. Lett., 2014,16, 3716–3719. [Link]
3.  Yu Wei, Huarong Tang, Xuefeng Cong, Bin Rao, Chao Wu* and Xiaoming Zeng*
       Pd(II)-Catalyzed Intermolecular Arylation of Unactivated C(sp3)–H Bonds with Aryl Bromides Enabled by 8-Aminoquinoline Auxiliary
       Org. Lett., 2014,16, 2248–2251. [Link]
4.   Bin Rao and Xiaoming Zeng*
       Aminocyanation by the Addition of N–CN Bonds to Arynes: Chemoselective Synthesis of 1,2-Bifunctional Aminobenzonitriles
       Org. Lett., 2014, 16, 314–317. [Link]
5.   Xuefeng Cong,§ Huarong Tang,§ Chao Wu*, and Xiaoming Zeng*
       Role of Mono-N-Protected Amino Acid Ligands in Pd(II)-Catalyzed Dehydrogenative Heck Reactions of Electron-Deficient (Hetero)Arenes: Experimental and Computational Studies
       Organometallics, 2013, 32, 6565–6575.  [Link]
6.   Yu Wei, Jinghua Tang, Xuefeng Cong and Xiaoming Zeng*
       Practical Metal-Free Synthesis of Chalcone Derivatives via a Tandem Cross-Dehydrogenative-Coupling/Elimination Reaction
       Green Chem. 2013, 15, 3165–3169. [Link]
7.   Xiaoming Zeng*
       Recent Advances in Catalytic Sequential Reactions Involving Hydroelement Addition to Carbon–Carbon Multiple Bonds
       Chem. Rev. 2013, 113, 6864–6900. [Link]
8.   Xiaoming Zeng, Laurean Ilies, and Eiichi Nakamura*
       Synthesis of Functionalized 1H-Indenes via Copper-Catalyzed Arylative Cyclization of Arylalkynes with Aromatic Sulfonyl Chlorides
J. Am. Chem. Soc. 2011, 133, 17638. [Link]
9.    Xiaoming Zeng, Rei Kinjo, Bruno Donnadieu, Guy Bertrand*
        Serendipitous Discovery of the Catalytic Hydroammoniumation and  Methylamination of Alkynes
Angew. Chem., Int. Ed. 2010, 49, 942. [Link]
10.   Xiaoming Zeng, Guido D. Frey, Rei Kinjo, Bruno Donnadieu, Guy Bertrand*
        Synthesis of a Simplified Version of Stable Bulky and Rigid Cyclic (Alkyl)(amino)carbenes, and Catalytic Activity of the Ensuing Gold(I) Complex in the Three-Component Preparation of 1,2-Dihydroquinoline Derivatives
J. Am. Chem. Soc. 2009, 131, 8690. [Link]  

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支持一下，好文章。