2011年-正在开发或即将上市的抗肿瘤药物

行走江湖

nearly 900 Medicines and vaccines in testing
offer Hope in the fight against cancer

    Few things cause patients more fear and apprehension than a cancer diagnosis. But today—because of early detection and a steady stream of new and improved treatments—cancer increasingly can be managed and even beaten. President Obama has called for a cancer cure in our lifetime, patients and their families are looking for more and better treatments, and America’s pharmaceutical research and biotechnology companies
are responding.
    Biopharmaceutical researchers are now working on 887 medicines for cancer. Many are high-tech weapons to fight the disease, while some involve innovative research into using existing medicines in new ways. The medicines in development—all in either clinical trials or under Food and Drug Administration review—include among others 98 for lung cancer, the leading cause of cancer death in the United States, and 91 for breast cancer, which is expected to strike more than 200,000 American women each year. The medicines indevelopment also include 80 for prostate cancer, which is expected to kill more than 32,000 American men each year, and 55 for colorectal cancer, the third most common cancer in both men and women in this country.
    A deep commitment to patients and research is at the core of the remarkable progress made in fighting cancer that has led to declines in cancer deaths. According to the National Cancer Institute, cancer deaths in the United States decreased 1.6 percent per year from 2001-2006.Meanwhile, the number of cancer survivors living in the United States has increased from 3 million in 1971 to 11.7 million in 2007. The increase in survivors is
attributed in large measure to earlier diagnosis and detection and better treatments and follow-up care.
    America’s pharmaceutical research companies are working on many new cutting edge approaches to fight cancer. They include:
• A medicine that interferes with the metabolism of
cancer cells by depriving them of energy from glucose.
• A medicine designed to induce a powerful immune
response to melanoma.
• A potential first-line treatment (meaning it’s given to
patients before any other treatment) and first-in-class
medicine designed to target specific cancer cells and
kill them, then activate the patient’s general immune
system to destroy any remaining cancer cells.
• A therapy that uses new nanotechnology that enhances
the delivery of medicine to the patient, overcoming
obstacles in existing treatments.
    Despite progress, cancer remains the second leading cause of death by disease in the United States, exceeded only by heart disease. In 2010, some 569,490 Americans were expected to die of cancer—more than 1,500 people a day. The hundreds of new medicines to treat cancer now being developed by the biopharmaceutical research industry demonstrate our commitment to meeting patient needs. They are our best hope for lessening the burden
of cancer to patients, their families and society.

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